Morphologic study and syntheses of type I collagen and fibronectin of human periodontal ligament cells cultured on poly(ethylene-co-vinyl alcohol) (EVA) with collagen immobilization

2000 ◽  
Vol 54 (2) ◽  
pp. 241-246 ◽  
Author(s):  
Chunyan Peng ◽  
Sadami Tsutsumi ◽  
Kazuaki Matsumura ◽  
Naoki Nakajima ◽  
Suong-Hyu Hyon
Keyword(s):  
Vinyl Alcohol ◽  
Periodontal Ligament ◽  
Type I Collagen ◽  
Periodontal Ligament Cells ◽  
Type I ◽  
Morphologic Study ◽  
Human Periodontal Ligament Cells ◽  
Poly Ethylene ◽  
Collagen Immobilization ◽  
Cells Cultured

scholarly journals Effects of Daidzein on the Production of Type I Collagen and Matrix Metalloproteinase1 by Stretched Human Periodontal Ligament Cells

2018 ◽  
Vol 17 (1) ◽  
pp. 27-32
Author(s):  
Masaru Yamaguchi ◽  
Erika Nakayama ◽  
Mami Shimizu ◽  
Jun Kikuta ◽  
Satoshi Horihata ◽  
...  
Keyword(s):  
Periodontal Ligament ◽  
Type I Collagen ◽  
Periodontal Ligament Cells ◽  
Type I ◽  
Human Periodontal Ligament Cells

Asiaticoside Induces Type I Collagen Synthesis and Osteogenic Differentiation in Human Periodontal Ligament Cells

2012 ◽  
Vol 27 (3) ◽  
pp. 457-462 ◽  
Author(s):  
Nunthawan Nowwarote ◽  
Thanaphum Osathanon ◽  
Peachaya Jitjaturunt ◽  
Sukuman Manopattanasoontorn ◽  
Prasit Pavasant
Keyword(s):  
Osteogenic Differentiation ◽  
Periodontal Ligament ◽  
Collagen Synthesis ◽  
Type I Collagen ◽  
Periodontal Ligament Cells ◽  
Type I ◽  
Human Periodontal Ligament Cells

Sphingomyelin Phosphodiesterase 3 Enhances Cytodifferentiation of Periodontal Ligament Cells

2016 ◽  
Vol 96 (3) ◽  
pp. 339-346 ◽  
Author(s):  
S. Miyauchi ◽  
J. Kitagaki ◽  
R. Masumoto ◽  
A. Imai ◽  
K. Kobayashi ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Periodontal Ligament ◽  
Type I Collagen ◽  
Alveolar Bone ◽  
Skeletal Development ◽  
Aggressive Periodontitis ◽  
Periodontal Ligament Cells ◽  
Type I ◽  
Phosphodiesterase 3 ◽  
Pdl Cells

Sphingomyelin phosphodiesterase 3 ( Smpd3), which encodes neutral sphingomyelinase 2 (nSMase2), is a key molecule for skeletal development as well as for the cytodifferentiation of odontoblasts and alveolar bone. However, the effects of nSMase2 on the cytodifferentiation of periodontal ligament (PDL) cells are still unclear. In this study, the authors analyzed the effects of Smpd3 on the cytodifferentiation of human PDL (HPDL) cells. The authors found that Smpd3 increases the mRNA expression of calcification-related genes, such as alkaline phosphatase (ALPase), type I collagen, osteopontin, Osterix (Osx), and runt-related transcription factor (Runx)-2 in HPDL cells. In contrast, GW4869, an inhibitor of nSMase2, clearly decreased the mRNA expression of ALPase, type I collagen, and osteocalcin in HPDL cells, suggesting that Smpd3 enhances HPDL cytodifferentiation. Next, the authors used exome sequencing to evaluate the genetic variants of Smpd3 in a Japanese population with aggressive periodontitis (AgP). Among 44 unrelated subjects, the authors identified a single nucleotide polymorphism (SNP), rs145616324, in Smpd3 as a putative genetic variant for AgP among Japanese people. Moreover, Smpd3 harboring this SNP did not increase the sphingomyelinase activity or mRNA expression of ALPase, type I collagen, osteopontin, Osx, or Runx2, suggesting that this SNP inhibits Smpd3 such that it has no effect on the cytodifferentiation of HPDL cells. These data suggest that Smpd3 plays a crucial role in maintaining the homeostasis of PDL tissue.

Surface modification of poly(ethylene-co-vinyl alcohol): hydroxyapatite immobilization and control of periodontal ligament cells differentiation

Biomaterials ◽  
2004 ◽  
Vol 25 (19) ◽  
pp. 4817-4824 ◽  
Author(s):  
Kazuaki Matsumura ◽  
Suong-Hyu Hyon ◽  
Naoki Nakajima ◽  
Hiroo Iwata ◽  
Akira Watazu ◽  
...  
Keyword(s):  
Surface Modification ◽  
Vinyl Alcohol ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cells ◽  
Poly Ethylene ◽  
And Control
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